Name factors underlying the increase in adverse reactions in the geriatric population: {Ans: • Polypharmacy • Severe illness, • multiple pathologies, • greater use of drugs that have a low therapeutic index • Inadequate supervision • Poor patient adherence}Sam, aged 65, is started on L-dopa for his PD. He asks why this is necessary. You respond: A. L-dopa is neuroprotective B. The primary goal of therapy is to replace depleted stores of dopamine C. This is the only drug that can provide symptomatic benefit D. This is the initial monotherapy drug {Ans: B. The primary goal of therapy is to replace depleted stores of dopamine}What are subtypes of cholinergic and adrenergic receptors? {Ans: • Cholinergic: nicotinic and muscarinic • Adrendergic: Alpha 1, alpha 2, beta1, beta 2, and dopamine}Which of the following medications is given for acetaminophen overdose? A. Epinephrine B. Sodium Bicarbonate C. Acetylcysteine D. Diphenhydramine {Ans: C. Acetylcysteine}At what age are adult levels of renal function achieved? • A. 6 months B. 12 months C. 24 months D. 3 years old {Ans: B. 12 months}Alpha 2 function? {Ans: Minimal clinical significance}