Hearing Conservation - Exam 1 Review Exam With 100% Correct Answers.

What are the effects of excessive ROS? {Ans: -can damage DNA -can lead to breakdown of cell membrane -can break down proteins in the cell -can trigger cell death}Toxic levels of ROS can occur from what? {Ans: -ischemia/reperfusion -excitotoxicity -overdriving of the mitochondria -external sources (inhalants, herbicides, radiation) **all of these things can happen in the cochlea during noise exposure}What are the elements of effective hearing conservation programs? {Ans: -trained and qualified personnel -appropriate testing facilities -baseline audiograms -annual monitoring -appropriate record maintenance -use of PHPDs as needed}What happens to the OHC after noise exposure? {Ans: -stereocilia on OHC can be broken or fused -There can be noise induced damage to prestin, resulting in the loss of motility}How is frequency selectivity affected by noise? {Ans: broadened tuning curves with NIHL, reduces ability to discriminate freq, making speech recognition harder -broader envelope = more freq will result in that neuron undergoing a depolarization = ability to distinguish one frequency from another is decreased = decreased WRS}What happens to the capillaries after noise? {Ans: -due to excessive blood flow during noise, RBC spill out of capillary, there is a bursting and clogging of cells -eventually capillary