Advanced Pharmacology Nsg 533 |86 Questions| With Correct Answers.

What lifestyle modifications should be recommended? {Ans: -losing weight if overweight -elevating head of bed while asleep -eating smaller meals -avoid foods/meds that exacerbate gerd -stop smoking -stop drinking alcohol}Final thoughts on GERD: {Ans: â—¦Therapy for GERD other than acid suppression, including prokinetic therapy and/or baclofen, should not be used in GERD patients without diagnostic evaluation. â—¦For patients with partial response to once daily therapy with a PPI, tailored therapy with adjustment of dose timing and/or twice daily dosing should be considered in patients with night-time symptoms, variable schedules, and/or sleep â—¦In patients with partial response to PPI therapy, increasing the dose to twice daily therapy or switching to a different PPI may provide additional symptom relief. â—¦ Maintenance PPI therapy should be administered for GERD patients who continue to have symptoms after the PPI is discontinued, and in patients with complications including erosive esophagitis and Barrett's esophagus â—¦Histamine-receptor antagonists (H2RA) therapy can be used as a maintenance option in patients without erosive disease if patients experience heartburn relief. Bedtime H2RA therapy can be added to daytime PPI therapy in selected patients with objective evidence of night-time reflux if needed, but may be associated with the development of