Transdermal estrogen therapy has fewer adverse effects {Ans: The total dose of estrogen is greatly reduced (because the liver is bypassed). There is less nausea and vomiting. Blood levels of estrogen fluctuate less. There is a lower risk for DVT, pulmonary embolism, and stroke. Types: Emulsion (Estrasorb) Spray (Evamist) Gels (EstroGel, Elestrin, Divigel) Patches (Alora, Climara, Estraderm, Menostar, Vivelle-Dot, Oesclim )}How to initiate treatment (when in the cycle is it best to start- may vary based on the type of contraceptive) {Ans: Use is initiated on day 1 of the menstrual cycle, and one pill is taken daily thereafter. A backup contraceptive method should be used for the first 7 days.}monitoring for androgen therapy {Ans: Evaluation for epiphyseal closure ( marks the end of growth of that particular bone) should be done with radiographs every six months}Tx of bacterial vaginosis {Ans: Metronidazole, 500 mg PO 2 times/day × 7 days or Metronidazole gel (0.75%), 1 full applicator (5 g) intravaginally once/day × 5 days or Clindamycin cream (2%), 1 full applicator (5 g) intravaginally at bedtime × 7 days.}adverse effects of androgen therapy {Ans: Abuse of androgens has both physical and psychological side effects. testicular