Nurs-166 Exam 1 Quizzes And Kahoots Accurate 100%

A drug given by which route is altered by the first-pass effect? A. Sublingual B. Subcutaneous C. Oral D. Intravenous {Ans: C. Oral Medications absorbed in the stomach and small intestine travel through the portal system and are metabolized by the liver before they reach the general circulation.}A patient has been taking the selective serotonin reuptake inhibitor (SSRI) sertraline (Zoloft) for about 6 months. At a recent visit, she tells the nurse that she has been interested in herbal therapies and wants to start taking St. John's wort. Which response by the nurse is appropriate? A. "That should be no problem." B. "Good idea! Hopefully you'll be able to stop taking the Zoloft." C. "Be sure to stop taking the herb if you notice a change in side effects." D. "Taking St. John's wort with Zoloft may cause severe interactions and is not recommended." {Ans: D. "Taking St. John's wort with Zoloft may cause severe interactions and is not recommended." The herbal product St. John's wort must not be used with SSRIs. Potential interactions include confusion, agitation, muscle spasms, twitching, and tremors. The other responses by the nurse are inappropriate.}Sublingual nitroglycerine is affected by first-pass effect. True False