Pathophysiology is defined as not only the cellular and organ changes that occur with
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disease, but also the effects that these changes have on total body function.
Biologic agents (bacteria, viruses), physical forces (trauma, burns, radiation), chemical agents (poisons, alcohol), one's genetic inheritance, and nutritional excesses or deficiencies.
Risk factors can be categorized as congenital conditions (present at birth) or acquired defects
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