D399 HLTH 2500 Gerontology Comprehensive Final OA Guide Q & S 20241. Multiple Choice: Which theory suggests that aging is the result of the accumulation of random molecular damage? a) Wear and Tear Theory b) Free Radical Theory c) Genetic Control Theory d) Cellular Senescence Theory Correct Answer: b) Free Radical Theory Rationale: The Free Radical Theory posits that aging results from the damage caused by free radicals that are produced during normal cellular metabolism. 2. True/False: Telomere shortening is a reversible process. Answer: False Rationale: Telomere shortening is considered an irreversible aspect of aging, as each cell division results in the progressive loss of telomeric DNA. 3. Fill-in-the-Blank: The non-enzymatic reaction that results in the bonding of sugars to proteins, lipids, and nucleic acids, which is implicated in various aging-related diseases, is known as __________. Answer: Glycation Rationale: Glycation refers to the covalent bonding of a sugar molecule to a protein or lipid molecule without the controlling action of an enzyme. 4. Multiple Choice: Which hormone has been implicated in the aging process due to its effects on metabolism and inflammation? a) Estrogen b) Insulin c) Cortisol d) Thyroxine Correct Answer: b) InsulinRationale: Insulin plays a significant role in