Midterm Exam Perfect Solutions Relias Rn Pharmacology Exam Perfect Solutions

Histamine Receptor Antagonists: adverse effects {Ans: -sedation -dry mouth -tremor}match each symptom to hypothetically malfunctioning brain circuits: cognitive symptoms {Ans: dorsolateral prefrontal cortex}Prescribing Considerations (antipsychotics) {Ans: -Start with lowest dose, eval tolerance, then titrate dose -no evidence that high antipsychotic doses are more effective than standard doses -Dose adjustments should be made after two weeks of taking medication -Establish efficacy and an effective med dose before switching to a long-acting injectable (LAI). dose of LAI will be same as the effective oral dose. -Most antipsychotic side effects and adverse effects are dose-related.}limbic system {Ans: includes circuits that are associated with pleasure and reward}Dopamine pathway: mesolimbic {Ans: location: Ventral tegmental area (VTA) within midbreain to the nucleus accumbens (NA) in the limbic system function: regulates emotional behaviors & associated with reward, motivation, pleasure symptoms: overactivation causes (+) symptoms and may be a downstream consequence of prefrontal cortex dysfunction & glutamate activity in the hippocampus}appropriate first-line medication treatment information for anxiety disorder's: obsessive-compulsive disorder {Ans: Obsessive-compulsive disorder fluoxetine fluvoxamine sertraline paroxetine clomipramine Drug therapy for at least 1 year}