Rush - Advanced Pharmacology - Nsg 531 - Exam 1 Questions And Answers 2024/2025 Graded A

Simple diffusion - what has to be true? {Ans: -drug has to be lipid soluble -there has to be a concentration gradient present -if a drug is high in fat solubility it is not going to be very water soluble - these two properties balance each other out}how do you calculate loading dose? {Ans: volume x the plasma concentration that we are trying to reach or therapeutic range VCther}What do CYP inducers increase? {Ans: elimination}what is the goal of the CYP enzyme system? {Ans: to increase the polarity of a drug thus facilitating its excretion}Kd {Ans: k2/k1}what is the name of the enzyme that metabolizes ~50% of drugs {Ans: CYP3A}