Nbme Physiology Updated Exam With Complete Solutions 2023/2024

Telomere structure. {Ans: Planar G-quartet formed from tandem repeats. Telomere cap protects closed ends}Rapamycin {Ans: Activates autophagy, to alleviate misfolded proteins and prevent aggregation}PKM2 {Ans: Inhibits creation of pyruvate, and shifts to PPP.}IgE {Ans: Parasites and worm infections Mast cell sensitization Allergic and hypersensitivity responses}Viral structure {Ans: Protein coat Detects appropriate host cell, protects viral genome, delivers genome to correct site, and carries enzymatic activity (ex: polymerases).}Flap Endonuclease (FEN1 ) {Ans: Cleaves DNA flaps for ligase to work (3' overhand and 5' flap) after primer is removed by RNase H.}