Ventral tegmental area (VTA) {Ans: One of the major dopamine-producing areas of the brain}Prescribing Pearls-Stimulants {Ans: · An EKG is required if cardiac history is present in a first-degree relative. ​ · Blood pressure, height, and weight should be monitored regularly during treatment. Abrupt withdrawal after prolonged use can result in irritability and rebound symptoms. · When switching stimulants, discontinue the current medication and start the new medication at a starting dose the next day.}Memantine (Namenda) Metabolism {Ans: · Minimal inhibition of CYP450 enzymes CYP1A2, CYP2A6, CYP2C9, CYP2D6, CYP2E1, and CYP3A4 occurs, which means there are no pharmacokinetic interactions with medications metabolized by these enzymes}The etiology of AD {Ans: Neurons in the brains of clients who develop AD may also have genetic coding abnormalities associated with amyloid precursor protein, while mutations of at least three different chromosomes, 21, 14, and 1, are associated with early-onset AD}dextroamphetamine (Adderall)-Stimulant {Ans: · Available in immediate and extended-release formulations​ · Often dosed in AM (IR or XR) with a PM or PM PRN (IR) dose if medication effects diminish prior to the end of school, study, or the workday​ · Most abused and diverted prescription stimulants Class: dopamine, norepinephrine