Nu 578 Unit 3 Test With Complete Solution

Evolocumab {Ans: PCSK9 inhibitor antibodies. dramatically lower LDL. used for familial hypercholesterolemia. twice a month for familial. can be used for high LDL injected 1-2 times a month. VERY EXPENSIVE!!}Alteplase {Ans: binds to fibrin then activates plasminogen-plasmin. used for MI, stroke, massive PE. few SE, few allergic reactions, but very expensive!!! these drugs dissolve clots and work best when given in 6 hours of MI and 3 hours of stroke. chest pain must be present no more than 12 hours prior to administration. BLEEDS ARE MAJOR RISK OF USE! all patients should also be receiving an anticoagulant and an antiplatlet drug but not a glycoprotein}Fenofibrate {Ans: Lowers TG by decreasing VLDL. hepatic metabolism and renal excretion. AE: GI disturbances,. gallstones, liver injury}Calcium channel blockers for dysrhythmias {Ans: Verapamil Diltiazem blockade of calcium channels slow av nodal automaticity, delay av nodal conduction, reduction myocardial contractility. prolong PR interval Use: used for a fib and a flutter, can terminate SVT caused by av nodal conduction AE: bradycardia, hypotension, peripheral edema, heart failure, constipation DDI: can elevate digoxin, blockers increase risk for bradycardia, av block, HR}drugs for stable angina drugs for variant angina drugs for unstable {Ans: 1.