Pharmacokinetics involvesAbsorption:Distribution:Metabolism:Elimination:route of administration with the highest bioavailabilityavoids first-pass metabolismadministration has variable and erratic
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absorption. n
4. Steady state (SS)
Half-life of a drug is
Zero-order (nonlinear) pharmacokinetics
CYP3A4 substrate drugs
Drug development process involves these steps according to the FDA:
2. Medication safety organizations
Two basic type of ADRS:
85% to 90% of ADRS
Adverse drug reactions are usually preventable,
ADRS are not commonly reported;
Polypharmacy
Angiotensin converting enzyme inhibitors (ACEIS):
ACEIS
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