NUR 635 Advanced Pharmacology Midterm Review (Guaranteed Pass) Pt on heparin in hospital setting. Why start coumadin 2 days before dc? Because coumadin needs a couple days before it starts working. Angina: bc pts dev tolerance to long-acting nitroglycerine w/i 1 day. How to prevent? Pts must have 8hrs with no nitroglycerine every days. Hint: At night, remove nitro patch bc no risk of exertional angina Underlying cause of angina coronary disease, athlerosclerosis Why do we give aspirin in pts w/atherosclerosis? Aspirin is an antiplatelet.. Prevents the existing plaques from getting bigger. Prevents plaque rupture. Cardio protective, prevents stroke, MI, CVA What is prescribed for angina pts w/DM? ACE inhibitors to protect the kidneys and nervesSE of high doses of aspirin? Tinnitus: ringing ears Pt education regarding Plavix(clopidogrel bisulfate)? Anti-platelet med. S/sx bleeding: blood in stool or vomit, excessive bruising, abd pain uterine bld, back pain, petichae. Interactions with EVERYTHING: OTC, herbals, supplements Pts on coumadin? What are we watching for? INR to check therapeutic levels. Half life is long. Check 12hrs after taking. What can be caused if pt started on heparin? day4, ordering blood work to check platelet count to observe for THROMBOCYTOPENIA coumadin and childbearing aged females