Psychopharmacology Exam 1 Review| 52 Questions And Answers.

Behavioral tolerance {Ans: Getting used to having it behaviorally (addiction vs dependent)}Glomerulus (kidney) {Ans: Ball of capillaries (filter)}Tolerance {Ans: Less of a response due to repeated exposure}Cytochrome p450 {Ans: Most effected by psychoactive drugs}Steady state {Ans: Increase and decrease never falling below concentration you want}Binding {Ans: Binding to fat protein, lipid ect.}Pharmacokinetics {Ans: Route of admin, excretion, how the drug moves through the body & breaks down.}Pharmacodynamic tolerance {Ans: Changes in the nerve cell functioning compensating for continued presence of drug}Agonist {Ans: Increases effect, creates similar effect.}Psychoactive Substance {Ans: Influences functioning of brain affecting behavior altering experiences}Bile {Ans: Product from the gallbladder}Genetic polymorphism {Ans: Higher genetic probability of becoming addicted to a curtain drug. (genetic diff)}Types of tolerance {Ans: Cross, acute, pharmacodynamic, behavioral}Cellular tolerance {Ans: Up or down regulation. changing the way cell responds (pharmacodynamic tolerance)}Hepatic enzyme inhibition {Ans: Decreases hepatic enzymes. Drug stays in system longer. dangerous with SSRI's (increase dosage)}Ionization {Ans: Charge of particle. (you want neutral to pass)}Nephron (kidney) {Ans: Taking out water soluble through urine}Acute tolerance {Ans: Tolerance at on single administration}Therapeutic effect {Ans: Desired effect}Sensitization