Take Home Exam Chapter 11 Q&a 2024

What criteria is commonly used to define the elderly? {Ans: age greater than 70}The renal excretion of a drug is a combination of {Ans: glomerular filtration plus renal secretion minus urinary reabsorption.}Some drugs given to children require that a higher than normal adult dose be given. Why? {Ans: Children metabolize some drugs faster than adults.}What do these foods have in common: beer, red wine, yeast products, chicken livers, and aged cheeses? {Ans: They contain tyramine.}What do the following drugs share in common: acetaminophen, methotrexate, nitrofurantoin, phenytoin, aspirin? {Ans: They can be hepatotoxic}In chronic renal disease, the binding of acidic drugs is reduced because there is {Ans: a loss of albumin through glomerular filtration.}Induction and inhibition involves enzymes in the _________ system. {Ans: hepatic}In chronic renal disease, {Ans: the dosage of renally eliminated drugs should be decreased.}Metoclopramide will increase the gastric absorption of acetaminophen because metoclopramide {Ans: increases the rate of gastric emptying.}Elderly patients may experience more drug interactions than other populations because {Ans: they take more drugs because they have more chronic illness.}Decreased blood circulation can affect drug metabolism by {Ans: reducing drug clearance.}Which effect will the presence of