Practice Exam Test Questions

If the frequencies of alleles A and B are 0.2 and 0.6, respectively, what is the probability of an AA child in a mating of AB x AB parents? a. 0.004 b. 0.012 c. 0.25 d. 0.50 e. 0.80 {Ans: c. 0.25}In a flow cytometric crossmatch, what is the purpose of the forward scatter versus side scatter plot? a. Gate on live lymphocytes to the exclusion of other blood cells b. Determine the size and side scatter of the cell populations c. Distinguish T cells from B cells d. Quantify the level of anti-donor IgG antibody {Ans: a. Gate on live lymphocytes to the exclusion of other blood cells}A positive T cell crossmatch between an untransfused male recipient and non-beaded spleen cells from the donor is most likely due to a. Anti-Bw6 b. Macrophage contamination c. Auto antibodies d. CYNAP antibodies e. Anti-HLA-DQ antibodies {Ans: b. Macrophage contamination}Human serum accidentally contaminates the AHG stock solution. What is the expected effect in the AHH-CDC assay? a. No effect b. Decreased specificity and many false positive reactions c. Many false negative reactions d. Decreased CYNAP effect {Ans: c}Without a signed consent HIPAA prevents patient data from being released