Which Antipsychotics Are Considered First-Generation And Why Are They Used Less Often Than Second Generation Antipsychotics?

DiscussionStudent’s NameInstitutional AffiliationCourse Number and NameInstructor’s Name and TitleAssignment Due DateDiscussionAntipsychotic medicine – drugs, used to manage the symptoms of psychiatric disorders, is typically divided into two classes. They differ according their chemical structure and the principle of action. First-generation antipsychotics, developed in the 1950s, are based on dopamine receptor antagonists (DRA). They are called “typical antipsychotics”. Second-generation antipsychotics are serotonin-dopamine antagonists, defined as “atypical antipsychotics” (Abou-Setta, 2012).Although FGAs are more affordable and widespread medicine than SGAs, they tend to be prescribed in less-cases nowadays. The major reason for it is the fewer cases of extrapyramidal side effects in serotonin – dopamine reactions than in dopamine ones. FGAs have been proved to provoke bradykinesia, rigidity, tremor, dystonias, and akathisia while SGAs have rather lower risks of neurological symptoms (Abou-Setta, 2012). Still, they have related side effects, which concern the metabolic tract such as weight gain, obesity, hyperglycemia, and dyslipidemia (Guzman, 2020). It is rather questionable whether second-generation antipsychotics are more effective or just more comfortable for both practitioners and patients. According to the Clinical Antipsychotic Trials and