Patho of DVT {Ans: Accumulation of clotting factors leads to thrombus formation (often near a valve). Inflammation leads to further platelet aggregation. Thrombus grows proximally}orthostatic hypotension {Ans: decrease in SBP of at least 20, or decrease in DBP of at least 10 within 3 minutes of standing. -neurogenic, caused by ANS dysfunction -dizziness, blurring of vision, syncope, fainting -Tx: inc. salt intake, raise HOB, thigh-high stockings, erythropoietin, vomune, vasoconstrictors (midodrine)}Cheyne-Stokes respiration {Ans: alternating periods of slow, irregular respirations and rapid, shallow respirations, possibly along with periods of apnea - High PaCO2 needed to stimulate ventilation, but leads to tachypnea. When PaCO2 decreases, apnea occurs.}DNA and genetics {Ans: Genotype- individual's chromosomes- the blueprint Phenotype- the physical end results (eye color, hair color, blood type) -Human genome= 20,000 genes -97% of genes are noncoding DNA -3% codes for synthesis of 60,000-80,000 different proteins, enzymes, hormones, ion channels, cell membrane receptors -99.9% of DNA in humans is the same}Isolated systolic hypertension {Ans: High SBP, normal DBP -Associated with cardiovascular and cerebrovascular events, all age groups}Insulin resistance in HTN {Ans: -associated with endothelial injury and affects renal function, causing renal salt and water retention -Insulin resistance is associated