Advanced Pharmacology Exam Summary | Questions & Answers (Scored 98%) | Latest Update 2023

Benzodiazepine uses/indications {Ans: Similar actions however different doses/concentrations/combinations produce different actions thus have different uses Anxiety/panic disorders skeletal muscle relaxation seizures sedation for procedures (due to relaxation and amnesic properties)}Clopidogrel (Plavix) Platelet aggregation inhibitor: Indications {Ans: STEMI CVA}Labetelol Hcl (trandate) Alpha/beta adrenergic blocker, anti-hypertensive Contraindications {Ans: Conditions associated with severe or prolonged hypotension Overt cardiac failure 2nd or 3rd degree AV block Severe bradycardia Cardiogenic shock Asthma}6 rights to medication administration {Ans: RIGHT CLIENT RIGHT MEDICATION RIGHT DOSAGE RIGHT ROUTE RIGHT TIME RIGHT DOCUMENTATION}Rocoronium Bromide (zemuron) Non-depolarizing NM blocking agent MOA {Ans: Skeletal muscle relaxant : Prevents neuromuscular transmission by blocking the effect of acetylcholine (ACh) at the myoneural junction, thus blocking depolarization. Acetylcholinesterase inhibitors, such as neostigmine, antagonize this action.}Dopamine Hcl (inotropin) Adrenergic agonist, vasopressor, sympathomimetic Dose {Ans: 5 mcg/kg/min - 20 mcg/kg/min titrated up by 5 until the desired effect 0.5- 3 mcg/kg/min has vasodilation effects in renal/mesentery/coronary/intracerebral vascular beds 5-10 mcg/kg/min has B1 receptor activation 10-20 mcg/kg/min has increased peripheral vasoconstriction (alpha effects)}Lidocaine (xylocaine) Anesthetic, anti-arrhythmic, sodium channel blocker {Ans: Contraindications: Ventricular escape rhythms, Idioventricular rhythms Severe degrees of SA, AV, or intraventricular block Hypersensitivity to amide-type local anesthetics Stokes-adams