DDL Dosing Questions & Answers 2024 A+ 1 / 2 1. Cyclosporine - Prevention of allograft rejec- tion 2. Cyclosporine - Treatment of autoimmune disease 4-14 mg/kg/day BID 2.5 mg/kg/day BID 3. Tacrolimus - Kidney transplantation 0.2 mg/kg/day 4. Tacrolimus - Heart transplantation 0.075 mg/kg/day 5. Tacrolimus - Liver transplantation 0.1-0.15 mg/kg/day 6. Tacrolimus - Pediatric liver transplantation 0.15-0.2 mg/kg/day 7. Sirolimus - Low Immunological Risk 40kg LD 6 mg MD 2 mg 9. Sirolimus - High Immunological Risk LD 15 mg MD 5 mg/day 10. Mycophenolate - Kidney transplantation 1 g BID 11. Mycophenolate - Liver/Heart transplanta- tion 1.5 g BID 12. Mycophenolate - Pediatric transplantation 600 mg/m^2 13. Gentamicin/Tobramycin - Dosing 5-7 mg/kg/day 30-60 minute infusion or di- vided doses every 8-12 hours 14. Amikacin - Dosing 15-20 mg/kg/day 30-60 minute infusion or di- vided doses every 8-12 hours 15. Vancomycin - Dosing 10-15 mg/kg Typical dose is 1g InfusionDDL Dosing Questions & Answers 2024 A+ 2 / 2 16. Carbamazepine - Treatment of seizure dis- orders 6 years old over 60 minutes every 8-12 hours 10-20 mg/kg/day or 800-1200 mg/day at SS 15-25 mg/kg/day or 800-1200 mg/day at SS 18. Carbamazepine - Migraine prophylaxis 10-20 mg/kg/day BID