Acaai Review For The Allergy & Immunology Boards Chapter 1 Questions And Answers 100% Verified

ACAAI Review For the Allergy & Immunology Boards Chapter 1 Questions and Answers 100% VerifiedWhat is the hapten-carrier effect? – ANS: Small-molecule antigen requires covalent linkage to a larger carrier to stimulate adaptive immune response. The process is achieved in collaboration between hapten-specific B cells and carrier-specific T cells. This is the basis of developing conjugated vaccines.What are the common superantigens and related diseases? - ANS: SEB and SEC from Staphylococcus aureus cause food poisoning. TSST from Staphylococcus aureus and SPE-C from Streptococus pyogenes cause toxic shock syndrome.Which type of T cell recognizes lipid antigens and what molecule is involved? - ANS: Natural killer T (NKT) cells recognize lipid antigens, and the CD1 molecule is involved.Which antigens are T-cell dependent and which are T-cell independent? - ANS: Protein antigens are T-cell dependent. Polysaccharide, nucleic acid, and lipids are T-cell independent.What is the binding site for CD4 on the MHC class I molecule? What is the binding site for CD8 on the MHC class II molecule? - ANS: On the MHC class I molecule, α3 is the binding site for CD4. On the MHC class II molecule, β2 is the binding site for CD8Which chain makes up the peptide