JNC-8 (2014)AHA/ACC Guidelines (2017)DefinitionsNormal: 130 SBP or >80 DBP if history of CVD or >10% ASCVD risk. >140/90 if no clinical CVD and >>vasodilation, lower HR Peripheral edema, hypotension, NO grapefruit juice, HA, constipation, need BP and HR monitoring Alpha II agonists HTN Clonidine>>> decreases outflow to the heart and vessels, lowers BP and HR three Ds dizziness, dry mouth, drowsiness female gender shortness of breath hypertension Mary has significant symptoms during recurrent episodes of atrial fibrillation. She also has multiple risk factors for thromboembolism (age, female gender, and hypertension). Therefore, she is a candidate for lifelong anticoagulation due to these risks. Shortness of breath is not a risk factor for thromboembolism.Beta1 blockers HTN/angina/heartfailure/MI you have 1 Ma Metoprolol, atenolol>>>acts on beta receptors in the heart to lower BP and HR Fatigue, erectile dysfunction. DO NOT stop using medication abruptly Can mask signs of hypoglycemia, change positions slowly Non-selective beta blockers HTN/angina/arrythmia/MI Please listen carefully Propranol, labetalol, carvedilol (act on both beta1 in the heart, but beta2 in the lungs) Lowers BP and HR, also causes bronchospasm>>not to use with asthmatics Use caution when combining ACEIs with potassium-sparing diuretics due to an increased risk of hyperkalemia. ACEIs and ARBS will