Examining The Role Of Netosis In The Progressive Form Of Covid-19 Disease

Examining the Role of NETosis in the Progressive Form of COVID-19 DiseaseAbstractBackground: Neutrophils are perceived as a clinical hallmark of COVID-19. In severe cases of the disease, patients tend to portray high levels of neutrophils, which leads to the development of Neutrophil extracellular traps (NETs) in a process known as NETosis. Severe cases of COVID-19 have been in one way or the other linked to NETosis.Aim: To examine up-to-date knowledge on the role of NETosis in the progressive form of COVID-19.Materials and Methods: Methodological approaches of PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines were used to obtain the articles that were employed in this systematic review. Different search strings together with inclusion and exclusion criteria were applied to obtain the relevant research journals. Results: NETosis is quite high in patients with COVID-19. NETosis contribute to acute dysfunction of organs, cytokine storm, multiorgan failure, and thromboembolic complications, inflammation, and blood clotting in the course of COVID-19. NETosis also has an antagonistic role in COVID-19 progression. Discussion: NETosis plays a crucial role in the immunopathogenesis of COVID-19. Conclusion: NETosis is linked to severe implications of COVID-19.IntroductionHitherto, the coronavirus disease