Question 1Which drug below has an interaction with cigarette smoking and should be adjusted based on patients tobacco use/non-use?Response Feedback: Clozapine blood levels are significantly lowered by cigarette smoking and by other hepatic enzyme-inducers. Question 2Which of the following medications is best to AVOID in maintenance treatment of bipolardisorder and why?Response Feedback: As noted previously, antidepressants may contribute to an increase in mood episode frequency. Question 3Glia cells play a supportive role in the neuron. A few of the functions of the glial cells include providing nutrition, maintaining homeostasis, stabilizing synapses, and myelinating axons. The glial cells are categorized as microglia or macroglia. Of the macroglia cells, which one plays a role in myelinating axons, which may contribute to mood disorders if altered? Question 4Which of the following are NOT primary target(s) symptom for antipsychotic agents in schizophrenia?i. Depression, anxiety, demoralization, suicidality, excitability, and agitationii. Delusions, hallucinations, disorganized thoughtsiii. Affective flattening, alogia, avolition, anhedonia, social withdrawaliv. Attention, memory, and executive functionsResponse Feedback: For schizophrenia, the primary target symptoms for antipsychotic agents fall into three categories: psychotic symptoms (e.g., hallucinations, delusions, disorganization); agitation (e.g., distractibility,affective lability, tension, increased motor activity); and negative symptoms (e.g. apathy, diminished affect, social withdrawal, poverty of