Wunderlich Patho Exam 1 Review Cellular Adaptation Atrophy

Exam 1 ReviewCellular AdaptationAtrophy: Physiologic: thymus gland atrophy (childhood)o Can be both physiologic or pathologico Physiologic Ex: Thymus glade (childhood)o Pathological Bed rest. Mobility is huge. Get up and walk. That prevent the atrophy in the muscle. Hypertrophy: (increase in size of cell) Another cellular adaptation that can actually be beneficial is hypertrophy of myocardial cells such as in endurance training - this is referred to as physiologic hypertrophy. Versus Pathologic hypertrophy that occurs secondary to HTN. Physiologic hypertrophy Ex: endurance training Pathological hypertrophy Ex: hypertension - myocyte increase in sizeHyperplasia : (increase in # of cells) Compensatory: removal of 70% of liver - can regenerate in about 2 weeks. Pathological: endometrial hyperplasiao Increase in the number of cells Compensatory hyperplasia adaptation Ex: 70% of liver can be removed and still function. Can regenerate in about 2 - 4 weeks. Pathological hyperplasia Ex: endometrium hyperplasia - like endometriosis: impact a womens ability to reproduce and is very painful1 | P a g eMetaplasia: (replacement of cells) normal columnar ciliated epithelial cells of the bronchial lining have been replaced by stratified squamous epithelial cells. Can be reversed if irritant stopped.o Replacement of cells - normal cells are replaced. o Normal columnar