Make sure to review all footnotes on PowerPoint slides - such as review chartXYZModule 1Pathophysiology basics*Components of Pathophysiology Pathogenesis- development or evolution of a disease Etiology- The study of the causes and origins of disease Clinical Manifestation- signs and symptoms or evidence of disease Treatment Implications- strategies used to manage/ cure a disease, management of symptoms, and includes prevention methods Three levels of epidemiology areo Primary- altering susceptibility or reducing exposure for susceptible persons (Ex. Immunizations are the best primary way to prevent diseases)o Secondary- early detection, screening, and management of disease (Ex. Cancer screening and monthly breast exams; mammograms)o Tertiary - rehabilitation, supportive care, reducing disability, and restoring effective functioning. Pt is already dealing with the issue and we should try to help them recover. (Ex. PT\OT following stroke)oHomeostasis -what is it, how does it help us o Homeostasis is a state of equilibrium, of balance within the organism Allostasis - define/ whats different from homeostasiso Ability to successfully adapt to challenges o Getting the body back its homeostasis stageAllostatic overload - what does this mean to the body/individual?o inadequate adaption mechanisms or excessive allostatic load; results in inability to maintain homeostasiso Leads to various illness and disorders, both