NUR 2502 NUR2502: MULTIDIMENSIONAL CARE III / MDC 3 EXAM 1 STUDY GUIDE LATEST 2021/ 2022 RASMUSSEN UTERINE LEIOMYOMA WHAT IS IT? Uterine leiomyomas, also known as a uterine fibroids Common benign tumors of smooth muscle cells or myometrium. Composed of smooth muscle that is replaced by fibrous (collagen and fibronectin) connective tissue Growth is promoted by estrogen Estrogen is the most important stimulus for leiomyoma growth Recent findings suggest that volume and growth of myomas are also heavily progesterone dependent Distinct, firm and round Often occur in groups Classified according to location Intramural - within the muscular wall of uterus Subserous -on the outside surface of uterus Submucosal - on the inside of the uterus lining May be attached by stem, increased risk to torsion or infection) Can be located in cervix, or within ligaments Can detach from uterus, feeds of blood supply from abdominal organsRISK FACTORS 30 to 50 % of women over 30 years old have leiomyomas African Americans have 3 to 4 times higher chances of development when compared to Caucasian women, in AA women, fibroids develop at earlier ages Family history has a three fold risk Obesity, which is possibly due to the association between