3250 Exam #3 Key Concepts1. Status Epilepticus medication choice: Valium/Diazepam, Lorazepam/Ativan (benzodiazepines)2. Parkinsons clinical manifestationso Disease of movement due to lack of dopamine receptors leaving muscle movement altered o Antiparkingsons medications: levodopa-carbidopa (increases levels of dopamineo Anticholinergics (benzotropine-cogentin ): help reduce tremors, rigidity, and improve walkingo Clinical Manifestations of Parkinsons:> Tremor: shaking begins in a hand, pill-rolling is common> Bradykinesia : steps may become short and shuffling> Impaired posture and balance become stooped, lean forward (balance problems)> Rigidity muscle stiffness can occur (dont swing arms when walking) , > Loss of automatic movements: Blinking, smiling, and swinging arms whenwalking is diminished and even lost. Fixed staring expression and unblinking eyes. Others may no longer gesture or seem animated when they speak.> Speech changes - speak more softly, rapidly or in a monotone, sometimes slurring or repeating words, or hesitating before speaking.> Dementia: In the later stages of Parkinson's disease> Depression> Sleep problems: trouble falling asleep, may wake up frequently throughout the night, experience sudden sleep onset, called sleep attacks, during the dayo Menieres disease Abnormal or too much inner ear fluid balance in semicircular canals caused by malabsorption of the endolymphatic sac or blockage of the endolymphatic duct Manifestations include